11-8067-25

antibody from ABEOMICS Inc.
Targeting: KLF10 EGRA, TIEG, TIEG1
Provider product page for 11-8067-25

Antibody data

Product number
11-8067-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-KLF10 Antibody
Antibody type
Polyclonal
Description
Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant KLF10
protein (amino acids 11-221) was us
ed as the immunogen for this antibo
dy.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
KLF10 protein structure - 11-8067-25 shown in red.