ANK2

Ankyrin 2

CFAP87, FAP87, LQT4

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]

Ensembl	UniProt	RefSeq	Entrez
ENST00000264366 ENSP00000264366	I6L894		ANK2 287
ENST00000357077 ENSP00000349588	Q01484.214 Q01484	NP_001139.3 NP_001139	ANK2 287
ENST00000394537 ENSP00000378044	Q01484.214 Q01484	NP_066187.2 NP_066187 NP_001341175.1 NP_001341175 NP_001341194.1 NP_001341194 NP_001341154.1 NP_001341154	ANK2 287
ENST00000503271 ENSP00000423799	B7Z651		ANK2 287
ENST00000503423 ENSP00000421011	D6RHE1		ANK2 287
ENST00000504415 ENSP00000426994	H0YAG3		ANK2 287
ENST00000504454 ENSP00000424722	E9PHW9		ANK2 287
ENST00000505342 ENSP00000422498	H0Y8Y2		ANK2 287
ENST00000506344 ENSP00000422888	H0Y933		ANK2 287
ENST00000506722 ENSP00000421067	Q01484.214 Q01484	NP_001120965.1 NP_001120965 NP_001341181.1 NP_001341181	ANK2 287
ENST00000509550 ENSP00000426944	E9PCH6	NP_001341210.1 NP_001341210	ANK2 287
ENST00000510275 ENSP00000421023	A0A5K1VW73		ANK2 287
ENST00000511380 ENSP00000425775	D6RIY9		ANK2 287
ENST00000514167 ENSP00000422486	H0Y8X8		ANK2 287
ENST00000514960 ENSP00000422853	H0Y931		ANK2 287
ENST00000612754 ENSP00000482888	A0A087WZU3		ANK2 287
ENST00000634436 ENSP00000489091	A0A0U1RQN6		ANK2 287
ENST00000671704 ENSP00000500926	A0A5F9ZHR2	NP_001341196.1 NP_001341196 NP_001341190.1 NP_001341190	ANK2 287
ENST00000671727 ENSP00000500102	A0A5F9ZH70	NP_001341157.1 NP_001341157 NP_001341165.1 NP_001341165	ANK2 287
ENST00000671756 ENSP00000500712	A0A5F9ZHY6	NP_001341204.1 NP_001341204	ANK2 287
ENST00000671762 ENSP00000500954	A0A5F9ZI81	NP_001341161.1 NP_001341161 NP_001341164.1 NP_001341164	ANK2 287
ENST00000671793 ENSP00000499928	A0A5F9ZGZ1	NP_001373072.1 NP_001373072	ANK2 287
ENST00000671809 ENSP00000500872	A0A5F9ZI40		ANK2 287
ENST00000671825 ENSP00000500459	A0A5F9ZHJ6	NP_001341184.1 NP_001341184 NP_001341185.1 NP_001341185 NP_001341183.1 NP_001341183	ANK2 287
ENST00000671854 ENSP00000500833	A0A5F9ZI36	NP_001341186.1 NP_001341186	ANK2 287
ENST00000671882 ENSP00000499887	A0A5F9ZGZ5		ANK2 287
ENST00000671893 ENSP00000499986	A0A5F9ZH34	NP_001341206.1 NP_001341206	ANK2 287
ENST00000671906 ENSP00000499953	A0A5F9ZH19		ANK2 287
ENST00000671951 ENSP00000500528	A0A5F9ZHN0	NP_001341200.1 NP_001341200	ANK2 287
ENST00000671971 ENSP00000499832	A0A5F9ZGX3		ANK2 287
ENST00000672045 ENSP00000499959	A0A5F9ZH17	NP_001341174.1 NP_001341174	ANK2 287
ENST00000672068 ENSP00000499902	A0A5F9ZGY3		ANK2 287
ENST00000672088 ENSP00000499837	A0A5F9ZGS5	NP_001341178.1 NP_001341178	ANK2 287
ENST00000672090 ENSP00000500540	A0A5F9ZHN5		ANK2 287
ENST00000672177 ENSP00000500918	A0A5F9ZI73		ANK2 287
ENST00000672209 ENSP00000499982	A0A5F9ZH30		ANK2 287
ENST00000672221 ENSP00000500473	A0A5F9ZHL9	NP_001341193.1 NP_001341193	ANK2 287
ENST00000672240 ENSP00000500548	A0A5F9ZHS1	NP_001341166.1 NP_001341166	ANK2 287
ENST00000672246 ENSP00000499990	A0A5F9ZH35	NP_001341201.1 NP_001341201	ANK2 287
ENST00000672251 ENSP00000500580	A0A5F9ZHT8		ANK2 287
ENST00000672312 ENSP00000500378	A0A5F9ZHJ4	NP_001341191.1 NP_001341191	ANK2 287
ENST00000672315 ENSP00000500780	A0A5F9ZI15		ANK2 287
ENST00000672350 ENSP00000500420	A0A5F9ZHL3	NP_001341182.1 NP_001341182	ANK2 287
ENST00000672356 ENSP00000500544	A0A5F9ZHQ3	NP_001341189.1 NP_001341189	ANK2 287
ENST00000672362 ENSP00000500522	A0A5F9ZHQ5	NP_001341168.1 NP_001341168	ANK2 287
ENST00000672366 ENSP00000500937	A0A5F9ZI69	NP_001341187.1 NP_001341187 NP_001341202.1 NP_001341202	ANK2 287
ENST00000672402 ENSP00000500881	A0A5F9ZI56	NP_001341172.1 NP_001341172 NP_001341173.1 NP_001341173	ANK2 287
ENST00000672411 ENSP00000499979	A0A5F9ZH10	NP_001341211.1 NP_001341211	ANK2 287
ENST00000672502 ENSP00000499870	I6L894		ANK2 287
ENST00000672684 ENSP00000499943	A0A5F9ZH03	NP_001373085.1 NP_001373085	ANK2 287
ENST00000672696 ENSP00000499828	A0A5F9ZGS7		ANK2 287
ENST00000672731 ENSP00000500908	A0A5F9ZI53	NP_001341205.1 NP_001341205 NP_001373091.1 NP_001373091	ANK2 287
ENST00000672759 ENSP00000499881	A0A5F9ZHN0		ANK2 287
ENST00000672779 ENSP00000499869	A0A5F9ZGY1	NP_001341170.1 NP_001341170	ANK2 287
ENST00000672793 ENSP00000500150	A0A5F9ZHA1		ANK2 287
ENST00000672830 ENSP00000500222	A0A5F9ZHD2		ANK2 287
ENST00000672854 ENSP00000500311	A0A5F9ZHE2	NP_001341197.1 NP_001341197	ANK2 287
ENST00000672880 ENSP00000500866	A0A5F9ZI18		ANK2 287
ENST00000672915 ENSP00000500622	A0A5F9ZHV4		ANK2 287
ENST00000672930 ENSP00000499913	A0A5F9ZGY4		ANK2 287
ENST00000672934 ENSP00000500645	A0A5F9ZHT4		ANK2 287
ENST00000672955 ENSP00000500527	A0A5F9ZHR2	NP_001341195.1 NP_001341195	ANK2 287
ENST00000672965 ENSP00000499891	A0A5F9ZGX8		ANK2 287
ENST00000672986 ENSP00000499967	A0A5F9ZH38		ANK2 287
ENST00000672990 ENSP00000500275	A0A5F9ZHG3	NP_001341159.1 NP_001341159	ANK2 287
ENST00000673044 ENSP00000500933	A0A5F9ZI15		ANK2 287
ENST00000673048 ENSP00000500832	A0A5F9ZI16	NP_001341209.1 NP_001341209	ANK2 287
ENST00000673109 ENSP00000500265	A0A5F9ZHF7		ANK2 287
ENST00000673231 ENSP00000500111	A0A5F9ZH99	NP_001341208.1 NP_001341208	ANK2 287
ENST00000673240 ENSP00000499996	A0A5F9ZH39	NP_001341169.1 NP_001341169 NP_001341171.1 NP_001341171 NP_001341198.1 NP_001341198 NP_001341160.1 NP_001341160	ANK2 287
ENST00000673255 ENSP00000500423	A0A5F9ZHL5		ANK2 287
ENST00000673298 ENSP00000500245	A0A5F9ZHE4		ANK2 287
ENST00000673334 ENSP00000500854	A0A5F9ZI30		ANK2 287
ENST00000673353 ENSP00000500007	A0A5F9ZH18	NP_001341207.1 NP_001341207	ANK2 287
ENST00000673363 ENSP00000500539	A0A5F9ZHR8		ANK2 287
ENST00000673430 ENSP00000500269	A0A5F9ZHC9		ANK2 287
ENST00000673453 ENSP00000500112	A0A5F9ZH58	NP_001341203.1 NP_001341203	ANK2 287
ENST00000673536 ENSP00000500524	A0A5F9ZHM6		ANK2 287
ENST00000673546 ENSP00000500843	A0A5F9ZI08	NP_001341199.1 NP_001341199	ANK2 287
ENST00000673555 ENSP00000500947	A0A5F9ZI65		ANK2 287
ENST00000673573 ENSP00000500883	A0A5F9ZI46		ANK2 287
ENST00000673778 ENSP00000501302	A0A669KBJ6		ANK2 287
ENST00000673943 ENSP00000501090	A0A669KB19		ANK2 287

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000044443 ENSMUSP00000043765	Q8C8R3.150 Q8C8R3	NP_848770.2 NP_848770	Ank2 109676
ENSMUST00000182008 ENSMUSP00000138730	Q8C8R3.150 Q8C8R3		Ank2 109676
ENSMUST00000182025 ENSMUSP00000138157	S4R1B7		Ank2 109676
ENSMUST00000182062 ENSMUSP00000138279	S4R1M4		Ank2 109676
ENSMUST00000182064 ENSMUSP00000138620	S4R2F3	NP_001314867.1 NP_001314867	Ank2 109676
ENSMUST00000182078 ENSMUSP00000138753	S4R2R5	NP_001314868.1 NP_001314868	Ank2 109676
ENSMUST00000182118 ENSMUSP00000138323	S4R1Q5		Ank2 109676
ENSMUST00000182452 ENSMUSP00000138373	S4R1U2		Ank2 109676
ENSMUST00000182547 ENSMUSP00000138602	S4R2D6		Ank2 109676
ENSMUST00000182571 ENSMUSP00000138747	S4R2Q9		Ank2 109676
ENSMUST00000182610 ENSMUSP00000138231	S4R1I1		Ank2 109676
ENSMUST00000182711 ENSMUSP00000138781	S4R2T7		Ank2 109676
ENSMUST00000182959 ENSMUSP00000138251	S4R1J9		Ank2 109676
ENSMUST00000182994 ENSMUSP00000138089	Q8C8R3.150 Q8C8R3		Ank2 109676
ENSMUST00000183095 ENSMUSP00000138487	S4R241		Ank2 109676
ENSMUST00000189368 ENSMUSP00000140700	A0A087WRM9		Ank2 109676
ENSMUST00000211813 ENSMUSP00000148296	A0A1D5RLB2		Ank2 109676
ENSMUST00000238781 ENSMUSP00000158721	A0A571BDG9		Ank2 109676
ENSMUST00000239234 ENSMUSP00000159256	A0A668KLB0		Ank2 109676

More gene data

Top validated antibodies
Invitrogen Antibodies	33-3700	5 references	Monoclonal	WB EL ICC OA
Atlas Antibodies	HPA008007		Polyclonal	WB ICC IHC
antibodies-online	ABIN2485081	2 references	Monoclonal	WB ICC IHC
Antibodies Incorporated / NeuroMab	73-144		Monoclonal	WB ICC IHC
Novus Biologicals	NBP2-22407		Monoclonal	WB ICC IHC

	Antibody	Refs	Type
Invitrogen Antibodies 8 antibodies
	33-3700	5	Monoclonal
	PA5-82326		Polyclonal

Atlas Antibodies 2 antibodies
	HPA008007		Polyclonal
	HPA035970		Polyclonal

antibodies-online 180 antibodies
	ABIN2485081	2	Monoclonal
	ABIN2485082	2	Monoclonal

Antibodies Incorporated / NeuroMab 4 antibodies
	73-144		Monoclonal
	73-145		Monoclonal

Novus Biologicals 36 antibodies
	NBP2-22407		Monoclonal
	NBP2-33863		Polyclonal

LSBio 40 antibodies
	LS-C228729		Monoclonal
	LS-C228730		Monoclonal

OriGene 6 antibodies
	73-144		Monoclonal
	73-145		Monoclonal

Biorbyt 30 antibodies
	orb1148590		Monoclonal
	orb181708		Monoclonal

Acris Antibodies GmbH 2 antibodies
	AM03224PU-N		Monoclonal
	BM912		Monoclonal

QED Bioscience 1 antibody
	56518		Monoclonal

Abnova Corporation 1 antibody
	MAB12854		Monoclonal

Abbexa 11 antibodies
	abx440160		Monoclonal
	abx440441		Monoclonal

BioLegend 6 antibodies
	821505		Monoclonal
	821506		Monoclonal

Creative Biolabs 5 antibodies
	CBMAB-A2750-YC		Recombinant
	CBMAB-A2751-YC		Recombinant

Leading Biology 2 antibodies
	APR11409G		Monoclonal
	APR11410G		Monoclonal

Creative Diagnostics 2 antibodies
	DCABH-2533		Monoclonal
	CABT-B1486		Monoclonal

Aviva Systems Biology 1 antibody
	OASA00949		Monoclonal

MyBioSource 1 antibody
	MBS800058		Monoclonal

UC Davis/NIH NeuroMab Facility 4 antibodies
	73-144		Monoclonal
	73-145		Monoclonal

BioLegend (formerly Covance Antibody Products) 2 antibodies
	MMS-5246		Monoclonal
	MMS-5247		Monoclonal

Abgent 2 antibodies
	ALS15330		Monoclonal
	ALS16238		Monoclonal

MilliporeSigma / Merck KGaA 2 antibodies
	HPA008007		Polyclonal
	HPA035970		Polyclonal

Bioss 1 antibody
	bs-6967R		Polyclonal

RayBiotech, Inc. 1 antibody
	119-16929		Monoclonal

United States Biological 1 antibody
	167574		Monoclonal

ANK2

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ANK2

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