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Protein structure
ATP6V1C2
ATPase H+ transporting V1 subunit C2ATP6C2, VMA5
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN394259 |
5 references | Monoclonal |
WB
EL
IHC
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| Proteintech Group | 16274-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| NovoPro Bioscience Inc. | 108309 |
Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA002400GA01HU |
Polyclonal |
WB
EL
IHC
|
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| Affinity Biosciences | DF4605 |
Polyclonal |
WB
EL
ICC
|
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