Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
QPRT
Quinolinate phosphoribosyltransferaseQPRTase
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
|||||
| antibodies-online |  ABIN393358 |
5 references | Monoclonal |
WB
EL
IHC
|
|
| Novus Biologicals | H00023475-M01 |
3 references | Monoclonal |
WB
EL
IHC
|
|
| Invitrogen Antibodies | MA5-25200 |
1 references | Monoclonal |
WB
ICC
IHC
FC
|
|
| GeneTex | GTX83743 |
Monoclonal |
WB
ICC
IHC
FC
|
||
| Abnova Corporation | H00023475-M01 |
1 references | Monoclonal |
WB
EL
IHC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider