STING1

gene product
ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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FabGennix
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Leading Biology
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Abbiotec
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Sigma-Aldrich
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RayBiotech, Inc.
1 antibody