CABT-B10910
antibody from Creative Diagnostics
Targeting: PCDHA5
CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- CABT-B10910 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human PCDHA5 monoclonal antibody, clone 2F9
- Antibody type
- Monoclonal
- Description
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgM
- Antibody clone number
- 2F9
- Vial size
- 200 _l
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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