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Protein structure
LTA
Lymphotoxin alphaLT, TNFB, TNFSF1
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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| antibodies-online |  ABIN453171 |
2 references | Polyclonal |
WB
EL
IHC
FC
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| Atlas Antibodies | HPA007729 |
1 references | Polyclonal |
WB
IHC
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| GeneTex | GTX50003 |
1 references | Monoclonal |
WB
EL
ICC
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| Abnova Corporation | MAB8481 |
3 references | Monoclonal |
WB
ICC
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| Aviva Systems Biology | OAAB05102 |
Polyclonal |
WB
EL
IHC
FC
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