V2581

antibody from NSJ Bioreagents

Targeting: HLA-DQA1 CELIAC1, HLA-DQA

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

V2581

Provider

NSJ Bioreagents

Product name

HLA-DQ Antibody (MHC II)

Antibody type

Monoclonal

Antigen

The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.

Description

Protein G purified antibody

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

SPV-L3

Vial size

20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)

Storage

Store the HLA-DQ antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

References

Submitted references

An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses.

de Wolf C, van der Zee R, den Braber I, Glant T, Maillère B, Favry E, van Lummel M, Koning F, Hoek A, Ludwig I, van Eden W, Broere F
Arthritis & rheumatology (Hoboken, N.J.) 2016 Mar;68(3):639-47

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Determinants of gliadin-specific T cell selection in celiac disease.

Petersen J, van Bergen J, Loh KL, Kooy-Winkelaar Y, Beringer DX, Thompson A, Bakker SF, Mulder CJ, Ladell K, McLaren JE, Price DA, Rossjohn J, Reid HH, Koning F
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun 15;194(12):6112-22

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Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.

Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen BE, Nielsen CH, Milo R, Zeilig G, Lassmann H, Altmann DM, Ben-Nun A
The Journal of biological chemistry 2015 Jun 12;290(24):15260-78

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Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes.

Pathiraja V, Kuehlich JP, Campbell PD, Krishnamurthy B, Loudovaris T, Coates PT, Brodnicki TC, O'Connell PJ, Kedzierska K, Rodda C, Bergman P, Hill E, Purcell AW, Dudek NL, Thomas HE, Kay TW, Mannering SI
Diabetes 2015 Jan;64(1):172-82

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Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires.

Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM
Immunogenetics 2015 Feb;67(2):73-84

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Ex vivo peptide-MHC II tetramer analysis reveals distinct end-differentiation patterns of human pertussis-specific CD4(+) T cells following clinical infection.

Han WG, Helm K, Poelen MM, Otten HG, van Els CA
Clinical immunology (Orlando, Fla.) 2015 Apr;157(2):205-15

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Exploring T cell reactivity to gliadin in young children with newly diagnosed celiac disease.

Liu E, McDaniel K, Case S, Yu L, Gerhartz B, Ostermann N, Fankhauser G, Hungerford V, Zou C, Luyten M, Seidl KJ, Michels AW
Autoimmune diseases 2014;2014:927190

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Characterisation of tissue transglutaminase-reactive T cells from patients with coeliac disease and healthy controls.

Comerford R, Coates C, Byrne G, Lynch S, Dunne P, Dunne M, Kelly J, Feighery C
Clinical immunology (Orlando, Fla.) 2014 Oct;154(2):155-63

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Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors α4β7 and CCR9.

Parra M, Herrera D, Calvo-Calle JM, Stern LJ, Parra-López CA, Butcher E, Franco M, Angel J
Virology 2014 Mar;452-453:191-201