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GDF7
Growth differentiation factor 7BMP12
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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| Biorbyt |  orb752115 |
Other |
WB
EL
ICC
IHC
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| antibodies-online | ABIN393235 |
5 references | Monoclonal |
EL
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| St John's Laboratory | STJ97349 |
Polyclonal |
WB
EL
ICC
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA768769LA01HU |
Polyclonal |
WB
EL
IHC
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| Affinity Biosciences | DF4097 |
Polyclonal |
WB
EL
ICC
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