345501

antibody from BioLegend
Targeting: PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2
Provider product page for 345501
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
345501 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD273 (B7-DC, PD-L2)
Antibody type
Monoclonal
Antigen
Human B7-DC transfected cells
Description
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Clone MIH18 is reported to block PDL2.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C.
PDCD1LG2 protein structure - 345501 shown in red.