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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Western blot [1]
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- Product number
- BS2394 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2394, RRID:AB_1663513
- Product name
- Arrestin C (E374) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 350-400 of Human Arrestin-C.
- Description
- Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with ÉÇ-Arrestins and may regulate ÉÇ-Arrestin mediated signaling.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Arrestin-C (E374) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate
