ST3GAL1

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

Description

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

8 (133454848 - 133571940)

Ensembl ID

ENSG00000008513  (ver. 103.38)

Orthologs

Mouse St3gal1: ENSMUSG00000013846

UniProt

Q11201

neXtProt

NX_Q11201

Human splice variants
Mouse splice variants

Protein structure