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Protein structure
PRSS8
Serine protease 8This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Proteintech Group |  15527-1-AP |
9 references | Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-27977 |
1 references | Polyclonal |
WB
IHC
OA
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| GeneTex | GTX103976 |
1 references | Polyclonal |
WB
IHC
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| Novus Biologicals | NBP1-31592 |
1 references | Polyclonal |
WB
IHC
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| R&D Systems | AF4599 |
Polyclonal |
WB
IP
IHC
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