TNNC2

Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]

Description

troponin C2, fast skeletal type

Protein family

FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

20:q13.12 (45823214 - 45833745)

Ensembl ID

ENSG00000101470  (ver. 99.38)

Orthologs

Mouse Tnnc2: ENSMUSG00000017300

UniProt

P02585

neXtProt

NX_P02585

Human splice variants
Mouse splice variants