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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11003-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11003-1-AP, RRID:AB_2202516
- Product name
- TCOF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TCOF1 antibody (Cat. #11003-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus:Implications for p53 Regulation and Neurite Outgrowth.
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.
Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response.
Cell-fate determination by ubiquitin-dependent regulation of translation.
CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function.
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.
Hassan A, Iftinca M, Young D, Flynn R, Agosti F, Abdullah N, Defaye M, Scott MGH, Dufour A, Altier C
International journal of molecular sciences 2021 Feb 25;22(5)
International journal of molecular sciences 2021 Feb 25;22(5)
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.
Werner A, Baur R, Teerikorpi N, Kaya DU, Rape M
eLife 2018 Jul 12;7
eLife 2018 Jul 12;7
Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response.
Rawlinson SM, Zhao T, Rozario AM, Rootes CL, McMillan PJ, Purcell AW, Woon A, Marsh GA, Lieu KG, Wang LF, Netter HJ, Bell TDM, Stewart CR, Moseley GW
Nature communications 2018 Aug 3;9(1):3057
Nature communications 2018 Aug 3;9(1):3057
Cell-fate determination by ubiquitin-dependent regulation of translation.
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M
Nature 2015 Sep 24;525(7570):523-7
Nature 2015 Sep 24;525(7570):523-7
CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function.
Park A, Won ST, Pentecost M, Bartkowski W, Lee B
PloS one 2014;9(4):e95101
PloS one 2014;9(4):e95101
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.
Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):18631-6
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):18631-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11003-1-AP(TCOF1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using TCOF1 antibody 11003-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 11003-1-AP(TCOF1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
