BS7272

antibody from Bioworld Technology, Inc
Targeting: TCOF1 TCS, treacle
Provider product page for BS7272
Western blot
Immunohistochemistry

Antibody data

Product number
BS7272 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Treacle polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Treacle.
Description
Treacle is a serine/alanine-rich 1,411 amino acid nuclear phosphoprotein that interacts with upstream binding factor (UBF) and affects transcription of the ribosomal DNA gene. Treacle is also involved in early embryonic development, particularly in the craniofacial complex, and may play a role in nucleolarcytoplasmic transport. The Treacle protein contains three domains with unique N- and C-termini and a large central repeat domain. Mutations in TCOF1, the gene that encodes for Treacle, cause Treacher Collins-Franceschetti syndrome (TCS), a disorder characterized by defects in craniofacial development. Symptoms of TCS include conductive hearing loss, hypoplasia of the mandible and maxilla, downward sloping palpebral fissures and cleft palate.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TCOF1 protein structure - BS7272 shown in red.