Tissue expression
Cell line expression
Protein structure
SSB
Small RNA binding exonuclease protection factor LaLa, La/SSB, LARP3
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Proteintech Group | 11720-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | CF500407 | Monoclonal |
WB
ICC
IP
IHC
FC
OA |
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OriGene | TA500406 | 1 references | Monoclonal |
WB
ICC
IP
FC |
|
GeneTex | GTX83560 | Monoclonal |
WB
ICC
IP
IHC
FC
|
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LSBio | LS-B10046 | Monoclonal |
WB
ICC
IP
IHC |
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Enhanced validation
Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider