Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13274-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13274-1-AP, RRID:AB_2083771
- Product name
- CPEB1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPEB1 antibody (Cat. #13274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory.
Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition.
Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer.
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development.
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
L-bodies are RNA-protein condensates driving RNA localization in Xenopus oocytes.
mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4.
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1.
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies.
MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins.
Block of CDK1-dependent polyadenosine elongation of Cyclin B mRNA in metaphase-i-arrested starfish oocytes is released by intracellular pH elevation upon spawning.
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.
CPEB1 promotes differentiation and suppresses EMT in mammary epithelial cells.
CPEB1 coordinates alternative 3'-UTR formation with translational regulation.
Chen CC, Han J, Chinn CA, Rounds JS, Li X, Nikan M, Myszka M, Tong L, Passalacqua LFM, Bredy TW, Wood MA, Lupták A
bioRxiv : the preprint server for biology 2023 Jun 9;
bioRxiv : the preprint server for biology 2023 Jun 9;
Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition.
Guo J, Zhao H, Zhang J, Lv X, Zhang S, Su R, Zheng W, Dai J, Meng F, Gong F, Lu G, Xue Y, Lin G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205500
Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer.
Zhou Y, Xiao L, Long G, Cao J, Liu S, Tao Y, Zhou L, Tang J
Frontiers in immunology 2022;13:921182
Frontiers in immunology 2022;13:921182
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development.
Xiong Z, Xu K, Lin Z, Kong F, Wang Q, Quan Y, Sha QQ, Li F, Zou Z, Liu L, Ji S, Chen Y, Zhang H, Fang J, Yu G, Liu B, Wang L, Wang H, Deng H, Yang X, Fan HY, Li L, Xie W
Nature cell biology 2022 Jun;24(6):968-980
Nature cell biology 2022 Jun;24(6):968-980
MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease.
Xiao G, Chen Q, Zhang X
Brain research bulletin 2021 Dec;177:282-294
Brain research bulletin 2021 Dec;177:282-294
L-bodies are RNA-protein condensates driving RNA localization in Xenopus oocytes.
Neil CR, Jeschonek SP, Cabral SE, O'Connell LC, Powrie EA, Otis JP, Wood TR, Mowry KL
Molecular biology of the cell 2021 Dec 1;32(22):ar37
Molecular biology of the cell 2021 Dec 1;32(22):ar37
mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4.
Pascual R, Segura-Morales C, Omerzu M, Bellora N, Belloc E, Castellazzi CL, Reina O, Eyras E, Maurice MM, Millanes-Romero A, Méndez R
RNA (New York, N.Y.) 2020 Dec 15;27(3):291-302
RNA (New York, N.Y.) 2020 Dec 15;27(3):291-302
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, Navarro P, Geschwind DH, Méndez R, Lucas JJ
Nature 2018 Aug;560(7719):441-446
Nature 2018 Aug;560(7719):441-446
Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1.
Lou WP, Mateos A, Koch M, Klussman S, Yang C, Lu N, Kumar S, Limpert S, Göpferich M, Zschaetzsch M, Sliwinski C, Kenzelmann M, Seedorf M, Maillo C, Senis E, Grimm D, Puttagunta R, Mendez R, Liu K, Hassan BA, Martin-Villalba A
Frontiers in molecular neuroscience 2017;10:445
Frontiers in molecular neuroscience 2017;10:445
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies.
Villanueva E, Navarro P, Rovira-Rigau M, Sibilio A, Méndez R, Fillat C
Nature communications 2017 Mar 16;8:14833
Nature communications 2017 Mar 16;8:14833
MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins.
Chen J, Cai T, Zheng C, Lin X, Wang G, Liao S, Wang X, Gan H, Zhang D, Hu X, Wang S, Li Z, Feng Y, Yang F, Han C
Nucleic acids research 2017 Apr 20;45(7):4142-4157
Nucleic acids research 2017 Apr 20;45(7):4142-4157
Block of CDK1-dependent polyadenosine elongation of Cyclin B mRNA in metaphase-i-arrested starfish oocytes is released by intracellular pH elevation upon spawning.
Ochi H, Aoto S, Tachibana K, Hara M, Chiba K
Molecular reproduction and development 2016 Jan;83(1):79-87
Molecular reproduction and development 2016 Jan;83(1):79-87
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
Calderone V, Gallego J, Fernandez-Miranda G, Garcia-Pras E, Maillo C, Berzigotti A, Mejias M, Bava FA, Angulo-Urarte A, Graupera M, Navarro P, Bosch J, Fernandez M, Mendez R
Gastroenterology 2016 Apr;150(4):982-97.e30
Gastroenterology 2016 Apr;150(4):982-97.e30
Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.
Giangarrà V, Igea A, Castellazzi CL, Bava FA, Mendez R
PloS one 2015;10(9):e0138794
PloS one 2015;10(9):e0138794
CPEB1 promotes differentiation and suppresses EMT in mammary epithelial cells.
Grudzien-Nogalska E, Reed BC, Rhoads RE
Journal of cell science 2014 May 15;127(Pt 10):2326-38
Journal of cell science 2014 May 15;127(Pt 10):2326-38
CPEB1 coordinates alternative 3'-UTR formation with translational regulation.
Bava FA, Eliscovich C, Ferreira PG, Miñana B, Ben-Dov C, Guigó R, Valcárcel J, Méndez R
Nature 2013 Mar 7;495(7439):121-5
Nature 2013 Mar 7;495(7439):121-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 13274-1-AP(CPEB1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CPEB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CPEB1. This antibody recognizes human,mouse,rat antigen. The CPEB1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.