Tissue expression
Cell line expression
Protein structure
SIVA1
SIVA1 apoptosis inducing factorCD27BP, SIVA, Siva-1, Siva-2
This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018]
Top validated antibodies |
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antibodies-online | ABIN1450104 | 4 references | Polyclonal |
WB
EL
ICC
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GeneTex | GTX32046 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | CF506823 | Monoclonal |
WB
ICC
IHC
|
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LSBio | LS-C144462 | Polyclonal |
WB
EL
ICC
|
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OriGene | TA506823 | Monoclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider