CECR2

This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Description

CECR2 histone acetyl-lysine reader

Tissue specificity

Tissue enhanced (brain, retina, skeletal muscle)

Subcell location

Nucleoplasm, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

22 (17359949 - 17558149)

Ensembl ID

ENSG00000099954  (ver. 103.38)

Orthologs

Mouse Cecr2: ENSMUSG00000071226

UniProt

Q9BXF3

neXtProt

NX_Q9BXF3

Human splice variants
Mouse splice variants

Protein structure