CSE1L

gene product
CAS, CSE1, XPO2
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
519 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
5 antibodies
Novus Biologicals
25 antibodies
Abnova Corporation
17 antibodies
Proteintech Group
2 antibodies
antibodies-online
128 antibodies
OriGene
14 antibodies
Acris Antibodies GmbH
11 antibodies
LifeSpan BioSciences, Inc.
38 antibodies
NovoPro Bioscience Inc.
11 antibodies
Invitrogen Antibodies
11 antibodies
Aviva Systems Biology
3 antibodies
Biorbyt
18 antibodies
Bioworld Technology, Inc
1 antibody
Abgent
10 antibodies
Boster Biological Technology
2 antibodies
Atlas Antibodies
2 antibodies
Arigo
4 antibodies
HUABIO Research
1 antibody
Signalway Antibody LLC
1 antibody
Bethyl Laboratories
3 antibodies
ProSci
3 antibodies
Affinity Biosciences
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
MyBioSource
10 antibodies
RabMAbs
4 antibodies
RayBiotech, Inc.
7 antibodies
Abbexa
6 antibodies
United States Biological
113 antibodies
Creative Diagnostics
9 antibodies
Leading Biology
11 antibodies
Creative Biolabs
23 antibodies
R&D Systems
1 antibody
Spring Bioscience
4 antibodies
St John's Laboratory
2 antibodies
Sigma-Aldrich
3 antibodies
Abbiotec
1 antibody