BS1080

antibody from Bioworld Technology, Inc
Targeting: CSE1L CAS, CSE1, XPO2
Provider product page for BS1080
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS1080 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1080, RRID:AB_1664131
Product name
CSE1L (E2) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids N-terminus of Human CSE1L.
Description
Normal tissues are characterized by a balance between cellular stasis, cell proliferation, cell differentiation and cell death. Aberrant regulation of any of these cell processes can result in cancer. Cell death during embryogenesis, tissue atrophy and normal tissue turnover is called apoptosis. This is characterized by cytoplasmic and nuclear condensation, nuclear disorganization and fragmentation of genomic DNA into 180-200 base pair oligomers. Several human cDNA fragments have been shown to render MCF-7 cells resistant to cell death induced by Pseudomonas exotoxin, Pseudomonas exotoxin-derived immunotoxins, diptheria toxin and tumor necrosis factor (TNF). One such fragment has proven to be the human homolog to the yeast chromosome segregation homolog, CSE1. Cloning of the full-length human cDNA has revealed a putative protein designated CAS, for cellular apoptosis susceptibility, that is 971 amino acids in length with 59% overall sequence homology as compared to yeast CSE1. CAS is highly expressed in testis and fetal liver.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CSE1L protein structure - BS1080 shown in red.