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Protein structure
PSMD3
Proteasome 26S subunit, non-ATPase 3P58, Rpn3, S3, TSTA2
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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| Proteintech Group |  12054-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 12054-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Novus Biologicals | 21980002 |
2 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN551808 |
3 references | Polyclonal |
WB
ICC
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| NovoPro Bioscience Inc. | 114399 |
Polyclonal |
WB
EL
IP
IHC
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