MED24

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Mediator complex subunit 24

Tissue specificity

Low tissue specificity

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

17 (40019097 - 40061215)

Ensembl ID

ENSG00000008838  (ver. 103.38)

Orthologs

Mouse Med24: ENSMUSG00000017210

UniProt

O75448

neXtProt

NX_O75448

Human splice variants
Mouse splice variants

Protein structure