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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL5643 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-SLC12A3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartters syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Reactivity
- Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100_g
- Concentration
- 1mg/mL
- Storage
- -20°C
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