AMM02583G

antibody from Leading Biology

Targeting: RXRB H-2RIIBP, NR2B2, RCoR-1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM02583G

Provider

Leading Biology

Product name

Retinoid X Receptor, β-Isotype Antibody

Antibody type

Monoclonal

Description

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Reactivity

Mouse, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

147

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.