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- Product number
- ABIN393473 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 1-272) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-272
- Isotype
- IgG
- Antibody clone number
- 1C12
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion.
Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1.
OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.
Defining the human deubiquitinating enzyme interaction landscape.
Edelmann MJ, Kramer HB, Altun M, Kessler BM
The FEBS journal 2010 Jun;277(11):2515-30
The FEBS journal 2010 Jun;277(11):2515-30
Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB
The Journal of biological chemistry 2010 Feb 12;285(7):4291-7
The Journal of biological chemistry 2010 Feb 12;285(7):4291-7
Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1.
Wang T, Yin L, Cooper EM, Lai MY, Dickey S, Pickart CM, Fushman D, Wilkinson KD, Cohen RE, Wolberger C
Journal of molecular biology 2009 Mar 6;386(4):1011-23
Journal of molecular biology 2009 Mar 6;386(4):1011-23
OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.
Stanisić V, Malovannaya A, Qin J, Lonard DM, O'Malley BW
The Journal of biological chemistry 2009 Jun 12;284(24):16135-45
The Journal of biological chemistry 2009 Jun 12;284(24):16135-45
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell 2009 Jul 23;138(2):389-403
Cell 2009 Jul 23;138(2):389-403
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Supportive validation
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
