60075-1-Ig

antibody from Proteintech Group

Targeting: SEPTIN2 DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

60075-1-Ig

Provider

Proteintech Group

Proper citation

Proteintech Cat#60075-1-Ig, RRID:AB_2187016

Product name

Septin 2 antibody

Antibody type

Monoclonal

Description

KD/KO validated Septin 2 antibody (Cat. #60075-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2F3B2

Vial size

20ul, 150ul

References

Submitted references

Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly.

Wang L, Paudyal SC, Kang Y, Owa M, Liang FX, Spektor A, Knaut H, Sánchez I, Dynlacht BD
Cell research 2021 Nov 15;

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Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors.

Li H, Saucedo-Cuevas L, Yuan L, Ross D, Johansen A, Sands D, Stanley V, Guemez-Gamboa A, Gregor A, Evans T, Chen S, Tan L, Molina H, Sheets N, Shiryaev SA, Terskikh AV, Gladfelter AS, Shresta S, Xu Z, Gleeson JG
Neuron 2019 Mar 20;101(6):1089-1098.e4

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A requirement for septins and the autophagy receptor p62 in the proliferation of intracellular Shigella.

Lobato-Márquez D, Krokowski S, Sirianni A, Larrouy-Maumus G, Mostowy S
Cytoskeleton (Hoboken, N.J.) 2019 Jan;76(1):163-172

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Septins suppress the release of vaccinia virus from infected cells.

Pfanzelter J, Mostowy S, Way M
The Journal of cell biology 2018 Aug 6;217(8):2911-2929

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Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts.

Farrugia AJ, Calvo F
Small GTPases 2017 Jan 2;8(1):49-57

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Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Calvo F, Ranftl R, Hooper S, Farrugia AJ, Moeendarbary E, Bruckbauer A, Batista F, Charras G, Sahai E
Cell reports 2015 Dec 29;13(12):2699-714

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A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.

Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, Noriega TR, Seol AD, Robinson JF, Bennett CL, Josifova DJ, García-Verdugo JM, Katsanis N, Hildebrandt F, Reiter JF
Nature genetics 2011 Jul 3;43(8):776-84

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human brain tissue were subjected to SDS PAGE followed by western blot with 60075-1-Ig(SEPT2 antibody) at dilution of 1:1000

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human brain using 60075-1-Ig(SEPT2 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human brain using 60075-1-Ig(SEPT2 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue