BS60482

antibody from Bioworld Technology, Inc
Targeting: CCL26 eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1
Provider product page for BS60482

Antibody data

Product number
BS60482 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CCL26 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in HumanCCL26.
Description
Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. C-C chemokines myeloid progenitor inhibitory factor-1 (MPIF)-1 and eotaxin-2 (also known as MPIF-2, CK b-6 or small inducible cytokine A24) both map to chromosome 7q11.23. MPIF-1 has chemotactic activity on dendritic cells derived from either peripheral blood monocytes or cord blood CD34+ progenitors. It is also a potent suppressor of bone marrow low proliferative potential colony-forming cells. Eotaxin-2, which promotes chemotaxis and Ca2+ mobilization in human eosinophils, exerts its activity solely through the CCR3 receptor. In addition, eotaxin-2 lacks suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors. A related C-C chemokine, eotaxin-3, shares only 33% amino acid identity with eotaxin-2, but shares many characteristics with eotaxin-2. Eotaxin-3 induces migration of eosinophils and basophils at a 10-fold higher concentration than eotaxin-2. The gene which encodes eotaxin-3 maps to human chromosome 7q11.23.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -23°C long term. Avoid freeze-thaw cycles.
CCL26 protein structure - BS60482 shown in red.