NSD1

gene product
ARA267, FLJ22263, KMT3B, STO
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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174 antibodies from 24 providers.

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Novus Biologicals
7 antibodies
antibodies-online
51 antibodies
Abnova Corporation
4 antibodies
Invitrogen Antibodies
5 antibodies
Antibodies Incorporated / NeuroMab
2 antibodies
LifeSpan BioSciences, Inc.
21 antibodies
Biorbyt
7 antibodies
Atlas Antibodies
3 antibodies
GeneTex
2 antibodies
OriGene
1 antibody
St John's Laboratory
2 antibodies
Creative Biolabs
9 antibodies
Abbexa
1 antibody
Abgent
1 antibody
Bethyl Laboratories
1 antibody
Boster Biological Technology
1 antibody
Signalway Antibody LLC
1 antibody
Creative Diagnostics
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
33 antibodies
MyBioSource
1 antibody
Sigma-Aldrich
1 antibody
UC Davis/NIH NeuroMab Facility
2 antibodies