RGS14

gene product
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
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Aviva Systems Biology
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Bethyl Laboratories
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Antibodies.com
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Abbkine Scientific Co.Ltd.
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Arigo
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Atlas Antibodies
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St John's Laboratory
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Creative Diagnostics
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Boster Biological Technology
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RabMAbs
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MyBioSource
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BioLegend (formerly Covance Antibody Products)
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United States Biological
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Leading Biology
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Sigma-Aldrich
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Abbexa
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Abgent
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EMD Millipore
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