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- References [5]
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- Western blot [3]
- Immunoprecipitation [1]
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- Product number
- 16258-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16258-1-AP, RRID:AB_2179918
- Product name
- RGS14 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RGS14 antibody (Cat. #16258-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.
Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?
14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4- signaling complex and RGS14 nuclear localization.
Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.
Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus.
Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR
The Journal of biological chemistry 2021 Jan-Jun;296:100024
The Journal of biological chemistry 2021 Jan-Jun;296:100024
Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?
Cinar E, Yalcin-Cakmakli G, Saka E, Ulusoy A, Yuruker S, Elibol B, Tel BC
Experimental neurology 2020 Aug;330:113357
Experimental neurology 2020 Aug;330:113357
14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4- signaling complex and RGS14 nuclear localization.
Gerber KJ, Squires KE, Hepler JR
The Journal of biological chemistry 2018 Sep 21;293(38):14616-14631
The Journal of biological chemistry 2018 Sep 21;293(38):14616-14631
Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.
Squires KE, Gerber KJ, Pare JF, Branch MR, Smith Y, Hepler JR
Brain structure & function 2018 Jan;223(1):233-253
Brain structure & function 2018 Jan;223(1):233-253
Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus.
Branch MR, Hepler JR
PloS one 2017;12(9):e0184497
PloS one 2017;12(9):e0184497
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:1500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RGS14 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RGS14. This antibody recognizes human,mouse,rat antigen. The RGS14 antibody has been validated for the following applications: ELISA, WB, IP analysis.
