Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- orb18078 - Provider product page
- Provider
- Biorbyt
- Proper citation
- Biorbyt Cat#orb18078, RRID:AB_10753996
- Product name
- Anti-HCRTR1 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit Polyclonal to HCRTR1. Orexins are endogeneous peptides that activate Orexin Receptor type 1 and type 2, two closely related G-protein coupled receptors. Orexins-A and -B are hypothalamic peptides derived from a precursor called preproorexin and affect the stimulation of food intake. They act on G protein receptors named orexin receptor-1 (OX1R) and orexin receptor-2 (OX2R), respectively.Stimulation of these receptors by orexins causes an increase in intracellular calcium levels in hypothalamic cells in vitro. In vivo, orexins control feeding and may also be involved in modulating sleep-wake cycles and other hypothalamic functions.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 μg
- Concentration
- Lyophilized Powder
- Storage
- Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western Blot analysis of rat brain tissue using Orexin R antibody
Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded rat brain tissue using Orexin R antibody