Tissue expression
Cell line expression
Protein structure
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1FLJ13335, ZFYVE7
The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020]
Top validated antibodies |
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Atlas Antibodies | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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