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Protein structure
CCR2
C-C motif chemokine receptor 2CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Novus Biologicals |  NBP1-48337 |
4 references | Polyclonal |
WB
ICC
IHC
FC
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| Proteintech Group | 16153-1-AP |
5 references | Polyclonal |
WB
EL
IHC
FC
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| GeneTex | GTX45788 |
7 references | Polyclonal |
WB
ICC
IHC
FC
|
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| Invitrogen Antibodies | PA5-23037 |
3 references | Polyclonal |
WB
ICC
IHC
FC
|
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| R&D Systems | MAB150-100 |
27 references | Monoclonal |
IHC
FC
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