KCNG3

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Description

Potassium voltage-gated channel modifier subfamily G member 3

Tissue specificity

Tissue enriched (brain)

Subcell location

Cytoplasmic bodies

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Voltage-gated ion channels

Chromosome

2 (42442017 - 42493982)

Ensembl ID

ENSG00000171126  (ver. 103.38)

Orthologs

Mouse Kcng3: ENSMUSG00000045053

UniProt

Q8TAE7

neXtProt

NX_Q8TAE7

Human splice variants
Mouse splice variants

Protein structure