ZFP90

This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]

Description

ZFP90 zinc finger protein

Tissue specificity

Low tissue specificity

Subcell location

Vesicles, Plasma membrane, Centrosome

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

16 (68530090 - 68576072)

Ensembl ID

ENSG00000184939  (ver. 103.38)

Orthologs

Mouse Zfp90: ENSMUSG00000031907

UniProt

Q8TF47

neXtProt

NX_Q8TF47

Human splice variants
Mouse splice variants

Protein structure