BS8285

antibody from Bioworld Technology, Inc
Targeting: GDAP1 CMT2K, CMT4, CMT4A
Provider product page for BS8285
Western blot
Immunohistochemistry

Antibody data

Product number
BS8285 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GDAP1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GDAP1.
Description
Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 (ganglioside-induced differentiation-associated protein 1) is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GDAP1 protein structure - BS8285 shown in red.