Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8442 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- WWP2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human WWP2.
- Description
- Atrophin interacting proteins (AIP)s bind to atrophin-1 in the vicinity of the polyglutamine tract. The WW domain consists of 35-40 amino acids and is characterized by four well conserved aromatic residues, two of which are tryptophan. All five AIPs contain multiple WW domains and can be divided into two distinct classes. AIP1 and AIP3 (WWP3) are MAGUK-like multidomain proteins containing a guanylate kinase-like region, two WW domains and multiple PDZ domains. AIP2 (WWP2), AIP4 (itchy) and AIP5 (WWP1) are highly homologous, each having four WW domains and a HECT domain characteristic of ubiquitin ligases. These interactors are similar to isolated Huntingtin-interacting proteins, suggesting commonality of function between two families of proteins responsible for similar diseases.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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