Tissue expression
Cell line expression
Protein structure
PTPRE
Protein tyrosine phosphatase receptor type EPTPE
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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OriGene | TA501028 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
|
LSBio | LS-C115045 | Monoclonal |
WB
ICC
IHC
|
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Invitrogen Antibodies | CF501028 | Monoclonal |
WB
ICC
IHC
FC |
||
GeneTex | GTX83761 | Monoclonal |
WB
ICC
IHC
FC |
||
Proteintech Group | 13922-1-AP | 1 references | Polyclonal |
WB
EL
IHC
|
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