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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 325106 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#325106, RRID:AB_756098
- Product name
- Biotin anti-human CD336 (NKp44)
- Antibody type
- Monoclonal
- Antigen
- recombinant human NKp44
- Description
- CD336 is also known as activating NK receptor NKp44 (NKp44), natural cytotoxicity triggering receptor 2, and lymphocyte antigen 95 homolog. It is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp44 has an apparent molecular weight of 44 kD and three isoforms are produced by alternative splicing. NKp44 is expressed on IL-2 activated NK cells and a subset of γ/δ T cells. NKp44 enhances NK cell mediated cytolysis of virus infected cells and tumor cells. NKp44 has been shown to associate with the intracellular adaptor DAP12.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C. Do not freeze.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human PBMCs were stimulated with rhIL-2 for 9 days, then stained with CD56 APC and biotinylated P44-8, followed by Sav-PE
- Conjugate
- Biotin
