Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM00037G - Provider product page
- Provider
- Leading Biology
- Product name
- Actin, Smooth Muscle (Leiomyosarcoma Marker) Antibody - With BSA and Azide
- Antibody type
- Monoclonal
- Description
- Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
- Reactivity
- Human, Mouse, Rat, Guinea Pig
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1A4; same as asm-1
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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