Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 23081-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- smooth muscle actin antibody
- Antibody type
- Polyclonal
- Description
- smooth muscle actin antibody (Cat. #23081-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A Novel End-to-End Biliary-to-Biliary Anastomosis Technique for Iatrogenic Bile Duct Injury of Strasberg-Bismuth E1-4 Treatment: A Retrospective Study and in vivo Assessment.
Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
Citri reticulatae Pericarpium attenuates Ang II-induced pathological cardiac hypertrophy via upregulating peroxisome proliferator-activated receptors gamma.
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth.
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Locus Coeruleus Degeneration Induces Forebrain Vascular Pathology in a Transgenic Rat Model of Alzheimer's Disease.
Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.
Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis.
Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis.
Effect of the vascular endothelial growth factor expression level on angiopoietin-2-mediated nasopharyngeal carcinoma growth.
Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
Ma D, Liu P, Lan J, Chen B, Gu Y, Li Y, Yue P, Liu Z, Guo D
Frontiers in surgery 2021;8:747304
Frontiers in surgery 2021;8:747304
Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells.
Nonoyama S, Karakida T, Chiba-Ohkuma R, Yamamoto R, Ujiie Y, Nagano T, Yamakoshi Y, Gomi K
Cells 2021 Nov 4;10(11)
Cells 2021 Nov 4;10(11)
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
An R, Wang X, Yang L, Zhang J, Wang N, Xu F, Hou Y, Zhang H, Zhang L
Toxicology 2021 Feb 15;449:152665
Toxicology 2021 Feb 15;449:152665
Citri reticulatae Pericarpium attenuates Ang II-induced pathological cardiac hypertrophy via upregulating peroxisome proliferator-activated receptors gamma.
Ni G, Wang K, Zhou Y, Wu X, Wang J, Shang H, Wang L, Li X
Annals of translational medicine 2020 Sep;8(17):1064
Annals of translational medicine 2020 Sep;8(17):1064
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth.
Krivanek J, Soldatov RA, Kastriti ME, Chontorotzea T, Herdina AN, Petersen J, Szarowska B, Landova M, Matejova VK, Holla LI, Kuchler U, Zdrilic IV, Vijaykumar A, Balic A, Marangoni P, Klein OD, Neves VCM, Yianni V, Sharpe PT, Harkany T, Metscher BD, Bajénoff M, Mina M, Fried K, Kharchenko PV, Adameyko I
Nature communications 2020 Sep 23;11(1):4816
Nature communications 2020 Sep 23;11(1):4816
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
Li Z, Zhu S, Liu Q, Wei J, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Cui H, Cheng Y, He Y, Cheng W, Zhao W, Zhao H, Zhou FH, Wang L, Dong J, Cai S
Molecular medicine reports 2020 Nov;22(5):3723-3734
Molecular medicine reports 2020 Nov;22(5):3723-3734
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Locus Coeruleus Degeneration Induces Forebrain Vascular Pathology in a Transgenic Rat Model of Alzheimer's Disease.
Kelly SC, McKay EC, Beck JS, Collier TJ, Dorrance AM, Counts SE
Journal of Alzheimer's disease : JAD 2019;70(2):371-388
Journal of Alzheimer's disease : JAD 2019;70(2):371-388
Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.
Chang Z, Yan G, Yan H, Zheng J, Liu Z
Life sciences 2019 Sep 15;233:116746
Life sciences 2019 Sep 15;233:116746
Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury.
Cui H, Banerjee S, Guo S, Xie N, Ge J, Jiang D, Zörnig M, Thannickal VJ, Liu G
JCI insight 2019 Feb 21;4(4)
JCI insight 2019 Feb 21;4(4)
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis.
Liang C, Li X, Zhang L, Cui D, Quan X, Yang W
Experimental and molecular pathology 2015 Oct;99(2):279-85
Experimental and molecular pathology 2015 Oct;99(2):279-85
Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis.
He Y, Wu YT, Huang C, Meng XM, Ma TT, Wu BM, Xu FY, Zhang L, Lv XW, Li J
Biochimica et biophysica acta 2014 Nov;1842(11):2204-15
Biochimica et biophysica acta 2014 Nov;1842(11):2204-15
Effect of the vascular endothelial growth factor expression level on angiopoietin-2-mediated nasopharyngeal carcinoma growth.
Chen HH, Weng BQ, Cheng KJ, Liu HY, Wang SQ, Lu YY
Vascular cell 2014 Mar 1;6(1):4
Vascular cell 2014 Mar 1;6(1):4
Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
He L, Zhou X, Qu C, Hu L, Tang Y, Zhang Q, Liang M, Hong J
Journal of cellular and molecular medicine 2014 Jan;18(1):49-58
Journal of cellular and molecular medicine 2014 Jan;18(1):49-58
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
Fan YF, Zhang R, Jiang X, Wen L, Wu DC, Liu D, Yuan P, Wang YL, Jing ZC
Cardiovascular research 2013 Aug 1;99(3):395-403
Cardiovascular research 2013 Aug 1;99(3):395-403
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 23081-1-AP(ACTA2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACTA2/smooth muscle actin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ACTA2/smooth muscle actin. This antibody recognizes human, mouse antigen. The ACTA2/smooth muscle actin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 23081-1-AP(ACTA2 antibody) at dilution of 1:500 (under 40x lens)
- Sample type
- tissue