DNPH1

This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008]

Description

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (43225629 - 43229481)

Ensembl ID

ENSG00000112667  (ver. 103.38)

Orthologs

Mouse Dnph1: ENSMUSG00000040658

UniProt

O43598

neXtProt

NX_O43598

Human splice variants
Mouse splice variants

Protein structure