TBC1D10C

The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

Description

TBC1 domain family member 10C

Tissue specificity

Group enriched (bone marrow, intestine, lymphoid tissue)

Subcell location

Nuclear bodies

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (67403915 - 67410089)

Ensembl ID

ENSG00000175463  (ver. 103.38)

Orthologs

Mouse Tbc1d10c: ENSMUSG00000040247

UniProt

Q8IV04

neXtProt

NX_Q8IV04

Human splice variants
Mouse splice variants

Protein structure