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Protein structure
SPOP
Speckle type BTB/POZ proteinBTBD32, TEF2
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  16750-1-AP |
51 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00008405-B01P |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | 16750-1-AP |
Polyclonal |
WB
ICC
IP
IHC
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| NovoPro Bioscience Inc. | 115581 |
Polyclonal |
WB
EL
ICC
IP
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| Wuhan Fine Biotech Co., Ltd. | FNab08189 |
Polyclonal |
WB
EL
IP
IHC
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