RFX4

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

Description

Regulatory factor X4

Tissue specificity

Group enriched (brain, testis)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

12 (106583004 - 106762803)

Ensembl ID

ENSG00000111783  (ver. 103.38)

Orthologs

Mouse Rfx4: ENSMUSG00000020037

UniProt

Q33E94

neXtProt

NX_Q33E94

Human splice variants
Mouse splice variants

Protein structure