ABIN2847219

antibody from antibodies-online

Targeting: FRAT1

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2847219

Provider

antibodies-online

Product name

anti-Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1) (AA 99-128), (Center) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 99-128, Center

Antibody clone number

RB14320

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.

Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD
The Journal of biological chemistry 2006 Nov 17;281(46):35021-9

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Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours.

Wang Y, Hewitt SM, Liu S, Zhou X, Zhu H, Zhou C, Zhang G, Quan L, Bai J, Xu N
British journal of cancer 2006 Mar 13;94(5):686-91

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Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.

Hino S, Michiue T, Asashima M, Kikuchi A
The Journal of biological chemistry 2003 Apr 18;278(16):14066-73

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC