GMEB1

This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]

Description

Glucocorticoid modulatory element binding protein 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

1 (28668778 - 28719353)

Ensembl ID

ENSG00000162419  (ver. 103.38)

Orthologs

Mouse Gmeb1: ENSMUSG00000028901

UniProt

Q9Y692

neXtProt

NX_Q9Y692

Human splice variants
Mouse splice variants

Protein structure