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Protein structure
DOCK4
Dedicator of cytokinesis 4FLJ34238, KIAA0716
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  21861-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Abnova Corporation | H00009732-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 21861-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| antibodies-online | ABIN564203 |
1 references | Monoclonal |
WB
EL
ICC
IHC
|
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| Novus Biologicals | H00009732-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
|
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